Kagocel manufacturer instructions for use. Antiviral drug Kagocel: effectiveness and dosage

The autumn-spring period is traditionally the heyday of infectious diseases. Decrease in air temperature, humid weather, lack of minerals, hypothermia - all these factors open the way for viral infections.

When symptoms of a cold appear, we invariably run to the pharmacy for life-saving drugs - antiviral, immunostimulating drugs and symptomatic therapy. After all, today, more than ever, time = money. Our mentality does not allow us to miss work, even if this may aggravate the course of SARS.

Thanks to the ubiquitous advertising, a pharmacy visitor can choose an over-the-counter cold medicine, for example, Kagocel tablets. Let's talk in more detail about all the pros and cons of this drug, consider how to take Kagocel for patients of different ages.

The active substance of the drug has a complex chemical name, which does not carry a special important information for patients. More interesting is that it is copolymer of gossypol with carboxymethyl cellulose.

Gossypol in its free chemical form is a natural yellow pigment derived from cotton. It is a protective substance that helps plants protect themselves from various pests and adverse external factors. Much attention was paid to this compound by scientists in the USSR, whose scientific research is the basis of the drug Kagocel.

It should be noted that the drug is completely domestic, since the production of the drug substance is also carried out in Russia. In 2015, Nearmedic Pharma produces Kagocel in Obninsk.

As additional components without medicinal activity are used: starch isolated from potatoes, polyvinylpyrrolidone, stearic acid calcium salt, milk sugar monohydrate.

Indications for the use of the drug

Contraindications

  • children under three years of age;
  • excessively high sensitivity and intolerance to any component of the tablets;
  • lack or absence of the lactase enzyme and, as a result, intolerance to lactose sugar (it is included in the tablets);
  • malabsorption syndrome - a decrease in the absorption capacity of the small intestine.

Kagocel during pregnancy

The drug should not be used when carrying a child (at any time) and during breastfeeding newborn. This limitation is due to the lack of necessary clinical studies.

You can get acquainted with drugs that are allowed to be used in pregnant women.

Method of application in children from 3 years

Kagocel can be used in children from the age of 3 years, since before that there is a high risk of getting the tablet into the respiratory tract.

Method of application in adults (from 18 years old)

Adults may use Kagocel to prevent infection and/or treat the following viral infections.

According to the manufacturer's data, the maximum concentration of interferon in the blood is reached after 48 hours. And an increase in the amount of circulating interferon means healing effect drug. The drug begins to act immediately after administration and reaches its maximum therapeutic effect on the second day. You may not defeat the virus in 1-2 days, but the increased concentration of interferon should significantly speed up the healing process.

Kagocel side effects

The only undesirable effect that may occur after taking this drug is the appearance of an allergic reaction to the ingredients of the tablets. No other side effects were reported.

Interaction with other chemical compounds

When combined with antibacterial, other antiviral and immunostimulating drugs, an additive effect is observed. In other words, their combination with Kagocel in no way affects the therapeutic effect of each other.

Kagocel and alcohol

It is strongly not recommended to combine the drug with alcoholic beverages. The fact is that the body is weakened during the illness and additional toxic loads at this time are useless to it. In addition, in combination with alcohol, the drug can show uncharacteristic side effects: increased fatigue, nervousness, lethargy, loss of attention, drowsiness during the day and insomnia at night.

Kagocel price

You can buy Kagocel in any pharmacy, as there is a steadily high demand for this drug on the Russian pharmaceutical market.

The medicine is produced in a package of 10, 20 or 30 tablets. The cost of the drug is acceptable for almost everyone. Price for the most common packages:

How much does kagocel cost?

  1. Kagocel 10 tablets - an average of 270 rubles.
  2. Kagocel 20 tablets - an average of 480 rubles.

Kagocel reviews

This drug is known to almost everyone due to its excellent marketing promotion among the population and medical professionals. The Minister of Health Tatyana Golikova was once engaged in a kind of promotion of this antiviral agent, asking him in Moscow pharmacies under the guns of television cameras (source: Golunov I. 13 most popular flu drugs: do they work?).

Some experts point to a weak evidence base for the effectiveness of the drug. In the public domain, as well as on the official resources of the Ministry of Health of the Russian Federation, there is no information about the results of clinical trials of the drug. In this case, you can easily find similar information for similar drugs-competitors. All this is a little confusing and alarming.

Of course, we will not dispute the effectiveness of this drug. The choice is always yours. We just wanted to highlight this problem with respect to some domestic drugs that have similar controversial issues in the field of proven clinical efficacy.

At the same time, despite everything, sales of the drug beat all records. He is annually among the top five best-selling remedies for our compatriots for colds, SARS and flu. So does it really work? If you have experience with Kagocel, please tell us about it in the comments. Many site visitors will be grateful to you!

Kagocel analogues of the drug

A distinctive feature of the drug is that there is no drug with the same active ingredient on the world pharmaceutical market. Kagocel is an original drug and does not have generics.

Of the drugs with a similar therapeutic effect, the following can be distinguished: Arbidol, Ergoferon, Grippferon spray and drops, Ingavirin, Remantadin, Cycloferon, Anaferon, Oscillococcinum, Amiksin, Viferon suppositories, Isoprinosine, Lavomax.

It is difficult to judge which is better than Kagocel. During the autumn-spring period, antiviral and immunostimulating agents are consumed by tons, if not thousands of tons. At the same time, they help someone, but not so much for someone. Incorrect diagnosis, violation of the drug regimen, individual characteristics of the body - all this ultimately affects the therapeutic effectiveness of drugs. Therefore, if Kagocel helps you, then you have found an inexpensive and effective remedy from colds, SARS and flu.

Kagocel: instructions for use and reviews

Kagocel is an immunomodulatory and antiviral drug.

Release form and composition

Kagocel is produced in the form of tablets: round, biconvex, from brown to cream color with patches (10 pcs in blister packs, 1 pack in a carton box).

The composition of 1 tablet includes:

  • Active substance: kagocel - 12 mg;
  • Auxiliary components: calcium stearate - 0.65 mg, potato starch - 10 mg, ludipress (direct compression lactose with the composition: lactose monohydrate, collidone 30 (povidone), collidone CL (crospovidone)) - to obtain a tablet weighing 100 mg.

Pharmacological properties

Pharmacodynamics

Kagocel induces the production of late interferons (a mixture of α- and β-interferons), which have a high antiviral activity. Kagocel stimulates the production of interferons in cell populations that form the body's antiviral response: macrophages, T-, B-lymphocytes, granulocytes, endothelial cells, fibroblasts. With oral administration of a single dose of Kagocel, the maximum values ​​of interferon titer in blood serum are reached after 2 days. The body's interferon response is characterized by a prolonged (4–5 days) circulation of interferons in the bloodstream. When Kagocel is taken orally, the dynamics of titers of circulating interferons does not correspond to the dynamics of accumulation of interferons in the intestine. In the intestine, the maximum production of interferons is achieved after 4 hours, and the production of interferons in the blood serum reaches high values ​​2 days after taking Kagocel.

When administered in therapeutic doses, the drug is non-toxic and does not accumulate in the body. It does not have teratogenic, mutagenic properties and embryotoxic effects, it is not carcinogenic.

In the treatment with Kagocel, the greatest efficiency is ensured when the drug is prescribed no later than on the fourth day from the onset of an acute infection. Kagocel can be used for prophylactic purposes at any time, including immediately after interaction with an infectious agent.

Pharmacokinetics

A day after administration, Kagocel accumulates mainly in the liver, and to a lesser extent in the thymus, lungs, kidneys, lymph nodes, and spleen. Low concentrations are noted in the heart, adipose tissue, testicles, muscles, blood plasma, brain. The low content of the active substance in the brain is observed due to the high molecular weight, which makes it difficult to penetrate the blood-brain barrier. The drug in the blood plasma is mainly in bound form.

In the case of daily repeated administration, the volume of distribution of Kagocel in the studied organs varies widely. The accumulation of the drug is especially pronounced in the lymph nodes and spleen. When taken orally, about 20% of the administered dose is present in the general circulation. The drug circulates in the blood mainly in the form associated with macromolecules: 47% - with lipids, 37% - with proteins. About 16% is the unbound part of the drug.

Kagocel is excreted from the body mainly through the intestines. After 7 days, 88% of the dose is excreted, of which 90% is excreted through the intestines, 10% by the kidneys. Not found in exhaled air.

Indications for use

  • Influenza and other acute respiratory viral infections (treatment and prevention in adults and children from 3 years old);
  • Herpes (treatment in adults).

Contraindications

  • Lactose intolerance, lactase deficiency, glucose-galactose malabsorption;
  • Age up to 3 years;
  • Pregnancy and lactation (breastfeeding);
  • Hypersensitivity to the components of the drug.

Instructions for use Kagocel: method and dosage

Kagocel is taken orally.

For adults, the drug is prescribed depending on the indications:

  • Treatment of acute respiratory viral infections (ARVI) and influenza: in the first 2 days of admission - 3 times a day, 24 mg (2 tablets), in the next 2 days, a single dose is reduced by 2 times (a total of 18 tablets per course);
  • Prevention of acute respiratory viral infections and influenza: 2 days of admission - 1 time per day, 24 mg, then a break for 5 days. Cycles of 7 days can be repeated (the duration of the prophylactic course varies from 7 days to several months);
  • Treatment of herpes: 3 times a day, 24 mg for 5 days (total 30 tablets per course).

For the treatment of SARS and influenza, children are prescribed:

  • 3-6 years: in the first 2 days of admission - 2 times a day, 12 mg (1 tablet), in the next 2 days - 1 time per day, 12 mg (total 6 tablets per course);
  • From 6 years: in the first 2 days of admission - 12 mg 3 times a day, in the next 2 days - 12 mg 2 times a day (10 tablets per course);
  • For the prevention of SARS and influenza, the drug should be taken in courses of 7 days for children: 2 days - 12 mg once a day, then a break for 5 days. Cycles of 7 days can be repeated (the duration of the prophylactic course varies from 7 days to several months).

Side effects

During the use of Kagocel, there may be side effects manifested as allergic reactions.

Before starting the use of Kagocel, as well as in cases of development of uncharacteristic symptoms, you should consult a doctor.

Overdose

special instructions

To achieve a therapeutic effect, it is recommended to start taking Kagocel no later than the fourth day after the onset of the disease.

According to the instructions, Kagocel goes well with antibiotics, immunomodulators and other antiviral drugs.

Use during pregnancy and lactation

It is forbidden to take the drug during pregnancy and breastfeeding, since there are no necessary clinical data on its safety for this category of patients.

Application in childhood

It is forbidden to use Kagocel for the treatment of patients under the age of 3 years.

drug interaction

During the simultaneous use of Kagocel with antibiotics, immunomodulators and other antiviral drugs, an additive effect is observed.

Analogues

Analogues of Kagocel are: Aveol, Aqua Maris, Bicyclol, Vasonat, Glyciram

Terms and conditions of storage

Store in a dark, dry place out of the reach of children at temperatures up to 25°C.

Shelf life - 2 years.

Kagocel is a drug (tablets), belongs to the category of antiviral drugs for systemic use. Important features from the instructions for use:

  • During pregnancy: contraindicated
  • When breastfeeding: contraindicated
  • In childhood: with caution

Package

Compound

The composition of 1 tablet includes:

  • kagocel (the main biologically active component) - 12 mg;
  • potato starch - 10 mg;
  • calcium stearate - 0.65 mg;
  • ludipress (directly compressed lactose, which is a mixture of lactose monohydrate, povidone (kollidon 30) and crospovidone (kollidon CL)) - up to 100 mg.

Release form

In pharmacy kiosks, the medicine can be found in the form of biconvex round tablets of cream or Brown color with small patches. The contour cell blister contains 10 pieces. 1 plate is included in the carton box.

pharmachologic effect

Kagocel (INN - International Nonproprietary Name) is an antiviral drug that is a synthetic complex organic sodium salt obtained by synthesis from water-soluble Carmoxymethylcellulose and Cottonseed Polyphenol. That is, the biologically active component of the drug is based on a certain proportion of plant compounds.

As an interferon inducer, Kagocel has the following therapeutic properties:

  • immunomodulatory;
  • antimicrobial;
  • antiviral;
  • radioprotective.

Wikipedia, the free encyclopedia of knowledge on the Internet, claims that the mechanism of action of a pharmaceutical drug is extremely simple. It is based on the ability of the components of the drug to stimulate the formation different types interferon, the body's natural defense proteins, since specific protein structures activate enzymatic systems to suppress harmful microflora and viral colonies. Also, interferons are able to suppress tumor activity in its germ. The sphere of influence of Kagocel extends to macrophages, T- and B-lymphocytes, granulocytes, endothelial cells and even fibroblasts.

Pharmacodynamics and pharmacokinetics

After a day (24 hours) has passed since the introduction of Kagocel into the body, the main biologically active components of the drug accumulate in the tissues of the liver, lungs, thymus, spleen, kidneys and lymph nodes, that is, organs that, to one degree or another, exhibit immune properties according to against harmful pathogens coming from outside. A low concentration of the constituent elements of the drug is observed in the myocardium of the heart and other muscles, adipose tissue, testicles, brain and blood plasma.

Serum interferon titer rises gradually and reaches its maximum figures 48 hours after the use of the tablets. In the intestine, the dynamics of accumulation of antiviral proteins is much higher - the maximum production of interferon is observed after 4 hours. Therefore, it is recommended to monitor the effectiveness of the drug by examining the contents of the lumen of the digestive tube and the activity of its cellular structures.

The therapeutic effect is characterized as long-term, since the response of interferons persists for 4-5 days, during which protective proteins continue to circulate in the bloodstream of the main and small vessels. Due to this property, the greatest efficiency in conservative treatment with a pharmaceutical preparation is observed when it is prescribed no later than the 4th day from the start. acute course infectious process.

Indications for use

  • flu;
  • acute respiratory viral infections;
  • prevention of colds;
  • herpes simplex in adult patients.

Contraindications

  • increased individual sensitivity to the constituent components of the pharmaceutical preparation;
  • the period of pregnancy and breastfeeding;
  • hereditary or acquired drug intolerance;
  • age category of patients up to 3 years;
  • enzymatic disorders digestive system- Lactase deficiency, lactose intolerance, glucose-galactose malabsorption.

Side effects

Adverse effects from the use of the drug are extremely rare and are usually limited to allergic reactions. However, if the patient observes any side effects of the active components of the pharmaceutical preparation, one should immediately seek the advice of a qualified doctor.

Instructions for use Kagocel (Method and dosage)

Tablets Kagocel, instructions for use

In the annotation, the manufacturer indicates that the drug should be used orally, without chewing the tablet, but swallowing it whole. You can drink enough liquid, but do not keep it for a long time oral cavity. The dosage and duration of treatment are usually selected individually empirically, but there are also general therapeutic regimens that should be considered by the attending physician as practical recommendations.

How to drink for adults?

With a therapeutic purpose in acute respiratory viral infections, influenza or influenza-like diseases, 2 tablets 3 times a day are prescribed for the first 2 days, and the next 2 days, 1 tablet 3 times a day. The course dosage is 18 tablets, and the duration of treatment is 4 days. How to take - before meals or after - for an adult body has no practical value, since the absorption capacity of the biologically active components of the pharmaceutical preparation does not change with the intake of food into the cavity of the gastrointestinal tract.

The drug can also be used as a prophylactic, preventive sanitation, which is carried out in 7-day cycles. The course is divided into two phases. The first, active, when 2 tablets are prescribed 1 time per day for 2 days, and the second, passive, is a 5-day break (the time during which the active ingredients are able to realize their therapeutic effects). Then, if necessary, you can repeat the preventive course of treatment.

Instructions for use for children

In the age category from 3 to 6 years - 1 tablet 2 times a day for the first 2 days, and for the next 2 days, 1 tablet 1 time per day. In total, the children's therapeutic course for the smallest is 6 tablets for a duration of 4 days.

At the age of more than 6 years, 1 tablet is prescribed 3 times a day for the first 2 days, and in the next 2 days - 1 tablet 2 times a day. Accordingly, the duration of conservative rehabilitation has not changed and is 4 days, and the dosage of the pharmaceutical preparation has increased to 10 tablets.

The drug can be used for prophylactic purposes and in pediatric practice. The biphasic regimen of the drug is maintained, however, the dosage is reduced to 1 tablet 1 time per day for the first 2 days.

How to take Kagocel with herpes?

Since the pharmaceutical action of Kagocel extends to viruses and the immune system, accordingly, the drug can be used by the adult category of patients not only to treat colds of viral etiology, but also to eliminate unpleasant herpes sores. How to drink tablets for herpes - 2 tablets are prescribed 3 times a day for 5 days. Heading dose - 30 tablets.

Overdose

As well as side effects, the clinical state of overdose is very rare and is accompanied by bouts of nausea and pain in the upper abdomen. In the event of the occurrence of these symptoms, it is recommended to clear the gastrointestinal tract from Kagocel tablets using artificially induced vomiting. Further, plentiful drinking and some other elements of detoxification therapy are prescribed.

Interaction

Clinically significant interactions on this moment has not been identified or described in the medical literature.

Terms of sale

The annotation to the drug claims that the tablets are freely available in pharmacy kiosks, that is, you can purchase the drug without an appropriate prescription.

Storage conditions

Keep the tablets out of the reach of children at a temperature not exceeding 25 degrees Celsius.

Best before date

special instructions

Is Kagocel an antibiotic or not?

The drug has strong antimicrobial, antiviral and immunomodulatory therapeutic effects, from which tablets can be perceived by ordinary people as an antibiotic. But from the side of clinical pharmacology, this is not entirely true, because in determining this group of pharmaceutical products, the key is the natural or semi-natural origin of the active ingredients. Kagocel, in turn, is a synthetic derivative of plant components, which allowed research scientists to combine best qualities cold medicines in one tablet.

Kagocel's analogs

Antiviral drugs are extremely large group pharmaceutical products, which, as a rule, occupy more than one shelf in pharmacy kiosks, respectively, Kagocel has a very wide list of analogues (analogues mean drugs with an identical international non-proprietary name or a similar code of the ATC system). To replace Kagocel can be used: Aveol, Aqua Maris, Bicyclol, Vasonat, Glyciram and many others.

Kagocel refers to expensive antiviral pills, so you should separately consider whether there is an analogue of Kagocel cheaper or not. The answer largely depends on the country of residence and the purchase of the drug. For example, in Ukraine, Abyufen, Avioplant, Atoxil, Bronchostop can be used as a medicine for respiratory diseases, the cost of which varies depending on the pharmacy chain, but always remains below the market price of Kagocel. AT Russian Federation a more accessible analogue is Anaferon.

Also, many pharmaceutical preparations are considered as analogs of Kagocel, which do not have an identical therapeutic effect, but are similar in the end result to an anti-cold antiviral drug.

Which is better: Kagocel or Ingavirin?

Ingavirin is a pharmaceutical drug popular in winter, characterized by a pronounced antiviral effect against the most common pathogens of acute respiratory diseases, such as influenza A and B viruses and influenza couple, respiratory syncytial group of viruses, adenovirus and many others. The mechanism of its action is based on the ability of biologically active components to influence the processes of reproduction and renewal of harmful agents. Also, the drug in the form of capsules is credited with a strong anti-inflammatory effect on the human body.

Undoubtedly, the pharmaceutical preparation is effective in the course of conservative rehabilitation of colds with a confirmed origin of the pathogen, however, as a non-specific therapy, when it is not possible to establish the etiological component of the pathology, the use of Ingavirin is not rational. Kagocel wins in another way, namely preventive measures, because the drug is actively used to prevent the development of respiratory infections in the winter, which, unfortunately, Ingavirin cannot boast of.

Which is better: Kagocel or Arbidol?

Arbidol, like Kagocel, is an antiviral drug, the therapeutic expediency of which is to increase the production of natural interferon, which opposes the invasion of pathological agents. In addition, the active components of the drug stimulate cellular and humoral immune responses, which positively affects the body's resistance to viral respiratory infections.

List side effects Arbidol is as short as that of Kagocel, but unlike the latter, the pharmaceutical preparation is included in list B (registry of drugs, the appointment of which should be done with extreme caution, since unforeseen complications may develop when they are used without careful medical supervision), which in itself is disturbing. If a decision is made to undergo conservative therapy or preventive rehabilitation "on the legs" (without an official sick leave), then Kagocel should definitely be chosen.

Which is better: Kagocel or Amiksin?

Amiksin is an effective synthetic interferon inducer, that is, the mechanism of action is similar to Kagocel tablets, since the drug increases the formation of an active antiviral agent by intestinal epithelial cells, hepatocytes, and some fractions of lymphocytes. Distinctive feature Amixin is the rate of onset of therapeutic effects, a mild immunomodulatory effect is observed already 4-24 hours after taking the drug. Accordingly, its use is more rational in urgent conservative sanitation of patients of the adult age category.

In pediatric practice, the pharmaceutical preparation has not gained such wide popularity, since the annotation contains a contraindication to the use of Amiksin tablets up to 7 years. This means that in the treatment of children of the younger age segment, preference should be given to Kagocel, the use of which can be started as early as 3 years.

Kagocel or Ergoferon - which is better?

Ergoferon is a drug with an unusually wide spectrum of therapeutic action, which, in addition to selective antiviral and immunomodulatory effects, includes antihistamine and anti-inflammatory components. The clinical rationality of the use of a pharmaceutical product has been proven on many counts. So, for example, the list of pathogens of respiratory infectious diseases that are defeated after using Ergoferon tablets is much larger than that of Kagocel.

Separately, it should be noted that Ergoferon can be used both in therapeutic practice for adult patients and in pediatrics, starting from the age of 6 months. Based on these facts, the pharmaceutical preparation can be recognized as better than Kagocel, but the price of analogues of this level is, of course, higher.

Kagocel for children

The pharmaceutical preparation is actively used in pediatric practice, since its therapeutic spectrum covers one of the widest parts of pediatric nosology. Acute respiratory diseases of infectious, bacterial or any other origin occur all the time, because Kagocel is prescribed for children from the age of 3. Annotation to the drug assures the safety of such an early use of the drug, and grateful reviews from parents only confirm this fact.

How to take it to children, you can find out in the paragraph with the instructions, where the exact dosages of the pharmaceutical preparation for different ages. You should also pay attention to the possibility of prophylactic use of the drug to prevent the development of colds and acute respiratory diseases, which are found everywhere in childhood.

Kagocel and alcohol

According to the mechanism of action and pharmacokinetic abilities of the active components of Kagocel, the drug does not directly interact with the components of alcoholic beverages. But endogenous interferons, produced under the influence of antiviral tablets, have a negative, inhibitory effect on the central nervous system. That is, immune agents are capable of provoking the development of certain psychological and neurological disorders (especially often - retinopathy, neuropathy, prolonged depression, and so on).

As a rule, such adverse effects of conservative treatment are manifested by asthenic disorders - excessive fatigue, weakness, drowsiness, reduced attention, impaired ability to concentrate, however, against the background of an acute respiratory disease, such side effects are not noticed, because they are similar to the clinical symptoms of almost any catarrhal nosological unit. .

If you mix alcohol and Kagocel, then such manifestations are mutually enhanced (the effect of alcoholic beverages on the central nervous system of a person is characterized by an inhibitory effect), therefore, at least 5 days must pass between the end of conservative treatment and the use of alcoholic beverages.

During pregnancy and lactation

Reliable clinical studies on the effect of the active components of a pharmaceutical preparation on the body of a woman and a child developing in her womb have not been conducted, therefore the decision to use the drug is made on an individual basis. Most practitioners are inclined to replace pills with other antiviral drugs during pregnancy and include this condition of the female body in contraindications to the use of Kagocel. A similar opinion of qualified specialists about breastfeeding - if possible, the use of this drug should be avoided.

  • Tamiflu
  • Cycloferon
  • The approaching season of viral infections is alarming for many mothers who want to protect their son or daughter from flu and colds. That is why in the autumn-winter period there is an increased demand for antiviral drugs, which include Kagocel.

    How does such a drug affect the child's body and does it harm? Is it allowed to give it to small children, for example, less than a year old? Is such a medication used for prophylactic purposes and with what drugs can it be replaced if necessary?

    Release form

    Kagocel has been produced by the domestic company Nearmedic Plus since 2003 only in tablet form. Syrups, capsules, powders, ampoules and other forms of the drug are not produced.

    There is also no separate pediatric form of the drug. Kagocel tablets have one dosage for all ages, and depending on the purpose of use and the age of the patient, only the regimen, the number of tablets per dose and the duration of the drug use change.

    The characteristics of the tablets are white-brown color, round shape, the presence of brown blotches. One pack may include 10, 20 or 30 of these tablets. Children most often buy the smallest package, since it is enough for one course of treatment, and for several weeks of prophylactic use.

    Compound

    The active substance of the drug is called Kagocel, which led to the name of the tablets. This synthetic compound is obtained by the fusion of plant molecules with nanopolymer molecules and is presented in a dosage of 12 mg per tablet. In addition, the compounds in the drug are calcium stearate, potato starch, crospovidone, lactose monohydrate and povidone. All these additional substances are considered harmless, but in some children they provoke allergies, so it is important for mothers of allergic children to know the composition of any medications.

    And now let's listen to the pediatrician regarding the drug Kagocel.

    Operating principle

    The drug is classified as an antiviral agent, since Kagocel has the ability to activate the production of alpha and beta interferons. These substances have a fairly strong antiviral activity, so they are synthesized in the human body during the immune response to a viral attack. The drug stimulates almost all cells of the immune system - B-lymphocytes, macrophages, granulocytes, T-cells and others.

    Taking Kagocel has the following effect:

    • Strengthens the body's defenses;
    • Restores immunity;
    • Accelerates the death of infectious agents;
    • Blocks the reproduction of viral cells;
    • Resists the formation of pathologically altered cells.

    The maximum level of interferons is noted in the patient's blood 48 hours after taking a single dose of Kagocel. The interferons produced in response to the use of the drug circulate in the bloodstream for up to 4-5 days.

    The drug itself penetrates the liver, lungs, spleen, lymph nodes and other organs. Most of the drug leaves the patient's body after 7 days, mainly with feces. Only 10% of the drug is excreted by the kidneys, so the diseases of this organ do not affect the use of Kagocel.

    The drug does not have a toxic effect and does not accumulate, and the greatest effect of its use is noted in situations where treatment is started in the first 3-4 days of an infectious disease. If the tablets are used for prevention, they can be drunk at any time, including the period after direct contact with a sick person who is excreting viruses.

    Indications

    Kagocel is prescribed for ARVI, herpes, influenza and other diseases caused by viruses. This drug is in demand in the treatment of tonsillitis, laryngitis, bronchitis and other diseases if they are caused by a viral infection. In addition, it can be prescribed as part of the complex treatment of rotavirus or enterovirus infection. The medication is also used to prevent infection with influenza viruses, rhinoviruses and other pathogens of acute respiratory infections.

    And now let's listen to Dr. Komarovsky about children's acute respiratory infections and SARS.

    At what age is it allowed to take?

    In pediatrics, Kagocel is used in children older than 3 years. Younger children (for example, if the child is only 2 years old) are not recommended to give this medicine. But even at the age of 3-5 years and older, Kagocel should not be self-medicated. Before treatment with any antiviral agents, you should consult a pediatrician to clarify whether there really are indications for such therapy.

    Contraindications

    The drug should not be taken:

    • Children who have an intolerance to any of its ingredients.
    • Babies with glucose-galactose malabsorption.
    • Small patients with lactase deficiency.
    • Adults during childbearing and breastfeeding.

    Side effects

    As in the treatment of many other drugs, the use of Kagocel may cause an allergic reaction. Apart from allergies, other negative effects from these pills are not mentioned.

    Instructions for use and dosage

    Tablets should be swallowed with water. It is not recommended to chew the medicine, and meals do not affect the regimen of the drug. With a therapeutic purpose, the following scheme of taking Kagocel is used:

    • For children 3-6 years old, the medication is prescribed for a 4-day course. In the first two days, the child is given 1 tablet twice a day, and then for two days the child takes one tablet once. In total, at this age, 6 Kagocel tablets are given for the entire period of treatment.
    • If a child is older than 6 years, then a four-day course is also prescribed for treatment, however, the frequency of administration is different and the course dose will be higher. A single dose is one tablet. On the first and second days of admission, a small patient is given it three times a day, and on the third and fourth days - twice. In total, the child receives 10 tablets of the drug in 4 days.

    In order to prevent viral infections, the medication in childhood is prescribed for a seven-day cycle. On the first day of treatment, a child older than three years is given 1 tablet of the drug per day, on the second day - another tablet of the drug once, and then Kagocel is not taken for five days, after which the cycle is repeated. The duration of such prophylactic use of the drug can be up to several months.

    Overdose

    Although Kagocel is considered a safe and non-toxic medicine, accidentally taking several tablets of such a medication at once can lead to abdominal pain, dizziness, severe nausea, and other signs of illness. Such an overdose requires the appointment of heavy drinking and provoking vomiting.

    Interaction with other drugs

    Together with Kagocel it is allowed to use other antiviral drugs. This drug also goes well with antibacterial agents and immunomodulatory drugs, enhancing their effectiveness.

    Terms of sale

    To purchase a package of Kagocel in pharmacies, a prescription from the attending physician is not required. The average price of 10 tablets is 220 rubles.

    Storage conditions and shelf life

    Keep Kagocel at home away from sunlight and moisture. The medicine should not be freely available to small children, and the storage temperature should not exceed +25 degrees. If the expiration date of the tablets, which is 4 years, has expired, it is absolutely impossible to give such a drug to a child.

    Reviews

    In most cases, mothers who gave Kagocel to children or took such pills on their own speak well of the medication. They emphasize the effectiveness of the medicine for colds and flu, as the general condition improved after the start of treatment and the disease passed more quickly. The drug is also praised for a minimum of contraindications, a small dosage and a short course of use.

    Obvious side effects in children from this drug, judging by the reviews, are extremely rare. The drug is well tolerated even by allergic children. The cost of the medicine is considered by most parents to be low, so rarely does anyone look for cheaper drugs. The release form does not cause difficulties in most patients. According to moms, the pills are easy to swallow and not bitter.

    As for the shortcomings of Kagocel, in some reviews they complain about the lack of its therapeutic effect, which is not associated with the action of the drug on all types of viruses. There are also complaints that after a treatment course for a child under 6 years of age, unused tablets remain. In addition, some mothers do not trust such a medicine, since its composition has not been fully deciphered.

    Analogues

    Replace Kagocel in viral diseases or for their prevention can be such drugs with antiviral and immunostimulating activity:

    • Orvirem. Such a medicine in syrup is allowed for children over 1 year old. Due to the presence of rimantadine in its composition, the drug actively fights influenza and other acute respiratory infections caused by viruses.
    • Amiksin. Such an antiviral drug in tablets contains tilorone. It is used in the treatment of influenza and other acute respiratory viral infections in children older than 7 years.
    • Viferon. The basis of such rectal suppositories is alpha-interferon. The drug is prescribed for ARVI, rotavirus, candidiasis, influenza and many other diseases. It can be used even in premature newborns. The drug is also produced in the form of a gel, allowed from birth, and an ointment prescribed for children older than a year.
    • Cytovir-3. This medicine based on alphaglutamyl-tryptophan, ascorbic acid and bendazole has an immunostimulating effect, therefore it is used both in the treatment of acute respiratory viral infections and for the prevention of influenza.
    • Amazonchik. The active substance of this drug is enisamium iodide. The medicine is produced in liquid form (syrup) and is in demand for acute respiratory viral infections in children over 3 years old.
    • Cycloferon. Such coated tablets activate the formation of interferons, therefore they help with influenza, herpes and other viral diseases. Children are prescribed from 4 years of age.
    • Arbidol. This domestic drug in suspension is prescribed for children over 2 years old, and in capsules and tablets - for children of three years and older. The basis of this drug is umifenovir, which has activity against coronaviruses and influenza viruses.

    Side effects of Kagocel and contraindications for use

    Usually, all symptoms disappear immediately after discontinuation of the drug or completion of the course. Allergic skin reactions, atopic rhinitis, slight irritability, mild muscle weakness may develop.

    There are contraindications for Kagocel, which should be considered before starting therapy.

    The list of contraindications for the use of this drug includes:

    • individual intolerance to the main components;
    • pregnancy and lactation;
    • early childhood up to 3 years.

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    Kagocel instruction

    Instructions for use of the drug Kagocel will acquaint the consumer with all the necessary information on using it for treatment. The accompanying sheet gives detailed description composition of the drug, and its dosage form, as well as informs about the terms and conditions of storage. In addition, the indications for use and methods for its implementation, the pharmacological action and the use of Kagocel by various categories of patients are outlined. Warning information is given about the side effects of the drug, contraindications and overdose. The instructions also provide information about the drug interactions of Kagocel with other medicines and provide feedback from patients who have already used it for treatment.

    Kagocel composition

    The active substance of the drug is the substance Kagocel in the required concentration, which is supplemented by auxiliary components in the amount necessary to obtain a tablet weight of 100 milligrams. For this, the substances of potato starch, calcium stearate and ludipress were taken.

    Kagocel release form

    The drug comes to pharmacies in the form of round biconvex tablets, which may have a creamy-brown color with inclusions. The container for the drug is cardboard packs, where a blister pack with a dozen tablets is placed.

    Terms and conditions of storage

    The drug can be stored in ordinary shaded dry rooms where the air temperature does not exceed 25 degrees. Storage and use of the drug is provided for two years. Children should not have access to Kagocel storage areas.

    Pharmacology

    Kagocel is an antiviral drug that induces interferon synthesis.

    Taking the drug can cause the body to form a mixture of alpha and beta interferons, which is called late interferon and has high activity against viruses.

    Kagocel produces interferon in each of the body's cell populations that take part in the antiviral response. The maximum value of interferon entering the blood serum with Kagocel can be achieved in two days. Therefore, the drug has such a lasting effect, because with its regular intake, the dynamics of interferon accumulation increases and it circulates in the bloodstream for at least four or five days.

    The therapeutic dose of Kagocel is non-toxic and has no ability to accumulate in the body. Mutagenic and tetratogenic properties of the drug were not found. It also has neither carcinogenic nor embryotoxic effects.

    If Kagocel was prescribed in the period up to the fourth day after the onset of an acute infection, the drug will still be able to effectively cope with it.

    In order to prevent the drug is suitable at any time, especially after there has been direct contact with the carrier of the infection.

    How to take Kagocel for children and adults dosage and recommendations

    It is worth talking about how to take "Kagocel" in various conditions that require increased immune defense and antiviral action. Tablets should be taken orally only, no other methods of use are provided by the manufacturer. Before taking the tablet, you can not break it, release it from the film shell, divide it into parts, grind it.

    Separately, it will be told about how to take "Kagocel" for children, since for this age group there are a number of practical restrictions. First of all, you should know that Kagocel can be given to children for preventive and therapeutic purposes after reaching the age of 3 years. A special dosage form is not produced for this, the standard dosage of the drug is used, taking into account the difference in the number of tablets taken per day and for the course of treatment.

    "Kagocel" for adults is initially recommended for admission in accordance with the therapeutic schemes proposed by the manufacturer. However, in the absence of positive dynamics in the patient's condition for 3 days, the dosage of "Kagocel" is selected individually, taking into account the parameters of the general condition of the body, body weight, age and other factors.

    Dosage of Kagocel for adults and children

    Treatment of acute respiratory viral infections, acute respiratory infections and influenza in adults

    Begins no later than 4 days from the onset of the disease. The first 2 days - 2 tablets 3 times at regular intervals. 3rd and 4th day 1 tablet 3 times a day

    Prevention of viral infections in adults

    1st and 2nd day 2 tablets 1 time per day, then 5 days the drug is not taken

    Treatment of viral infections in children aged 3 to 6 years

    The first 2 days, 1 tablet 2 times a day, the next 2 days, 1 tablet 1 time a day

    Treatment of viral infections in children aged 6 to 13 years

    The first 2 days, 1 tablet 3 times a day, the next 2 days, 1 tablet 2 times a day

    Prophylactic administration of the drug in children from 3 to 12 years

    1st and 2nd day 1 tablet 1 time per day, then 5 days the drug is not taken

    Side effects

    In the form of side effects on taking the drug, allergic reactions may occur, the occurrence of which should be reported to the doctor immediately.

    Overdose

    In case of an overdose of Kagocel, assistance should be provided to the victim in the form of prescribing a plentiful drink, followed by induction of vomiting.

    Drug Interactions

    Simultaneous administration of Kagocel with other antiviral drugs, as well as immunomodulating agents and antibiotics, can sum up their therapeutic effect.

    Additional instructions

    In order for a positive therapeutic effect to be obtained during therapy with Kagocel, its administration should be started no later than four days after the onset of the disease, if the moment of its occurrence was missed for treatment.

    The use of other antiviral drugs, as well as antibiotics and immunomodulating agents in the treatment of Kagocel is welcome.

    Cold tablets Kagocel Instructions for use, How to take it for adults and children

    Not a single person is immune from colds. Adults, children, the elderly and athletes can face a problem, so you need to know which drugs can quickly have a positive effect, relieve symptoms and act on the source.

    The drug Kagocel in the form of compact tablets for colds is an effective medication used in the main course of therapeutic effects, as well as for prophylactic use during the period of greatest risk of infection.

    Group - antiviral and immunomodulating agents.

    Composition and properties of Kagocel

    The constituent elements of Kagocel indicate its natural origin, the absence of components of chemical origin, reduce the likelihood of an allergic reaction and side effects. The main component that starts to work is kagocel. One tablet of this component contains 12 mg. Complementing the efficiency of work such substances as:

    calcium stearate (calcium salt and stearic acid);
    crospovidone (improves the release of substances, accelerates chemical reactions);
    a substance called povidone is an enterosorbent in its properties;
    lactose monohydrate (a component that people with intolerance to this substance should pay attention to).

    Additionally, the composition includes a natural and completely safe product - starch obtained from potatoes. The drug is packed in cardboard boxes and blisters. One contains 10 tablets and instructions on how to use the product to achieve maximum effectiveness.

    The main active ingredient (kagocel) is a unique composition that is aimed at stimulating natural substances. As a result of the synthesis launched by him, the body resumes (intensifies) the production of its own antiviral proteins, as well as interferons. The work is done intensively, but does not lead to negative processes.

    The main component is a preparation of biological synthesis - a combination of cotton polymer and cellulose, resulting in a complex sodium salt. The therapeutic effect in this case is mild, the action is direct and indirect.

    Since the effect is not intense, the medication can be used to treat colds, viral infections that occur in childhood.

    The maximum possible positive effect from the use of a cold medicine is observed if the therapeutic effect was started within the first 4 days from the onset of symptoms.

    Such an impact is directly related to the rapid spread of viruses inside cells, since during this period they are most sensitive and vulnerable to the effects of interferons directed at them.

    In accordance with the peculiarities of the work of interferon, Kagocel has the following medicinal properties:

    • elimination of microbes (any microorganisms cannot withstand the effects of the drug for a long time);
    • antiviral (viruses stop developing, weaken and die without causing serious harm to the body with the timely start of using the remedy);
    • strengthening the natural forces of the immune system;
    • radioprotective.

    About 20% of the active substance after the implementation of the necessary therapy to restore strength and the functioning of the immune system accumulates in the liver, but the drug is excreted through the gastrointestinal tract - up to 91% and the rest (about 10%) with liquids. The accumulation of the main component and excipients in the body during medical studies was not observed.

    Indications for use: features of the impact of the drug Kagocel

    Prophylactic or therapeutic use of Kagocel for colds shows good results - the recovery process is faster, the symptoms disappear 1-3 days after the start of treatment. In addition to the usual acute respiratory infections, the medication is included in the active recovery program for adults and children if diagnosed with:

    • diseases that have developed in the body due to the activity of viruses (ARVI);
    • influenza (including those accompanied by severe symptoms);
    • herpes (flowing in a simple form).

    Is it possible to take Kagocel during pregnancy and with alcohol

    Many patients are interested in how Kagocel and alcohol are combined with each other, because situations are not rare when the drug is taken for prophylactic purposes and various celebrations fall during this period. Also, some women think that Kagocel can be used during pregnancy to prevent and treat viral infections. And these two questions sometimes become cornerstone, so let's look at them in more detail.

    So, is it possible to take "Kagocel" during pregnancy and during breastfeeding, are such methods of therapy justified? The vast majority of doctors, based on the recommendations of researchers and manufacturers of the drug, recommend that expectant mothers, if possible, refrain from taking this drug. There is a risk of detrimental effects on the tissues of the developing fetus, and provoke immune disorders in the child, which in the future can lead to quite serious pathologies. This is due to the ability of the active substance to freely penetrate the placental barrier.

    As shown by clinical and laboratory studies, the concentration of the drug in breast milk is also large enough for there to be potential harm to a developing immune system baby.

    In this regard, during pregnancy, such methods of treatment should be excluded, and during breastfeeding, if necessary, taking the drug, you need to wean the baby from the breast for a period from the start of therapy and up to 7 days after taking the last dose.

    "Kagocel" and alcohol to take at the same time is also strictly prohibited. Stimulated production of interferons under the influence of ethyl alcohol can cause severe forms of retinopathy (blindness), neuropathy (limping), depressive syndrome with severe insomnia. In some cases, these changes are irreversible.

    You can take alcoholic beverages only 7 days after the completion of the full course of treatment.

    Kagocel analogues

    Like many medications Kagocel has many substitutes on the pharmaceutical market, which have a similar therapeutic effect. Strictly speaking, they cannot be considered analogues, since they have an active composition different from Kagocel, however, they take on this role due to the ability to provide such a therapeutic effect.

    Cheap analogues of Kagocel

    For those patients who find the drug Kagocel expensive, cheaper analogues can be purchased. Such preparations can also be found in any pharmacy. They are dispensed without a doctor's prescription and will help with colds no worse. Antiviral drugs "Arbidol" and "Anaferon" have pharmacological properties similar to those of Kagocel.

    Arbidol or Kagocel

    Among the many options for antiviral drugs, it is Arbidol that is by far the most popular drug that replaces Kagocel prescriptions. Both medicines have a similar therapeutic effect on the body in the fight against colds. Therefore, choosing between them can be quite difficult. Since both have a similar therapeutic effect and also have similar side effects, perhaps the patient can reserve the right to choose. However, many therapists are still inclined to believe that Kagocel can be recognized as a more established drug in the field of treatment and prevention of influenza and SARS.